ABSTRACT
<p><b>UNLABELLED</b>To evaluate the detection rate of myocardial bridging by 64-slice spiral CT coronary angiography.</p><p><b>METHODS</b>The data of 3011 patients with suspected coronary artery disease undergoing 64-slice spiral CT coronary angiography were collected and analyzed retrospectively.</p><p><b>RESULTS</b>A total of 174 cases (5.8%) with myocardial bridging were detected by 64-slice spiral CT coronary angiography, among which 168 (96.6%) had single foci of involvement and 6 (3.4%) had were multiple foci. Involvement of the left anterior descending coronary artery (LAD) was detected in 167 out of the 174 cases (96.0%). The length of the myocardial bridge varied between 5 and 120 mm (mean of 30.5 mm), and the depth of the tunneled artery ranged between 1.3 and 2.8 mm (mean 2.3 mm). Seventy-nine of the cases (45.4%) had uncomplicated myocardial bridging and 95 (54.6%) had myocardial bridging complicated by coronary atherosclerosis.</p><p><b>CONCLUSION</b>Multi-slice spiral CT coronary angiography is a reliable and noninvasive modality for diagnosis of myocardial bridging to allow direct measurement of the length and depth of the myocardial bridge and detection of concurrent coronary and cardiac lesions.</p>
Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , China , Epidemiology , Coronary Angiography , Methods , Coronary Artery Disease , Diagnostic Imaging , Myocardial Bridging , Diagnostic Imaging , Epidemiology , Retrospective Studies , Tomography, Spiral Computed , MethodsABSTRACT
<p><b>OBJECTIVE</b>To observe the protective effects of Cleistocalyx operculatus on lipid peroxidation in rat liver microsomes and on the trauma of PC12 cells induced by H2O2.</p><p><b>METHOD</b>The mouse liver homogenate lipid peroxidation assay and PC12 Cell culture and Cell viability (MTT assay) were applied.</p><p><b>RESULT</b>Cleistocalyx operculatus showed strong protective effects on lipid peroxidation in rat liver microsomes in a dose-dependent manner and exhibited potent protective effects on the trauma of PC12 cells induced by H2O2 (200 micromol x L(-1)) when the concentration reached 1.00 g x L(-1).</p><p><b>CONCLUSION</b>Cleistocalyx operculatus may be used as antioxidant to prevent or delay the pathogenesis of neural cell diseases.</p>